Phosphorus pentachloride → 2-Benzyl-3-chloro-5-methoxy-2H-1,2,4,6-thiatriazine-1,1-dioxide

HRID 1982168Notes

Reaction equation

HRID 1982168 reaction equation
[CH2:1]([N:8]1[C:13](=O)[NH:12][C:11]([O:15][CH3:16])=[N:10][S:9]1(=[O:18])=[O:17])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.P(Cl)(Cl)(Cl)(Cl)[Cl:20]>O=P(Cl)(Cl)Cl>[CH2:1]([N:8]1[C:13]([Cl:20])=[N:12][C:11]([O:15][CH3:16])=[N:10][S:9]1(=[O:18])=[O:17])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 136459252-Benzyl-5-methoxy-2H-1,2,4,6-thiatriazin-3-one-1,1-dioxide

Product 1

HCID 140505002-Benzyl-3-chloro-5-methoxy-2H-1,2,4,6-thiatriazine-1,1-dioxide

Reagents, catalysts & solvents 1

HCID 24813Phosphorus oxychlorideSolvent

Procedure

A stirred mixture of 2-benzyl-5-methoxy-2H-1,2,4,6-thiatriazin-3-one-1,1-dioxide (10.5 g) and PCl5 (12.2 g) in POCl3 (35 ml) is refluxed overnight. The reaction mixture is evaporated in vacuo at 50° C. affording the crude product as an oil.

Workup

  1. temperatureis refluxed overnight
  2. customThe reaction mixture is evaporated in vacuo at 50° C.

Sources & evidence

ORD record
ord-a26e4fd0992c45289367e3b8e590e514
Source dataset
uspto-grants-1986_06
Patent number
US04595683

Reaction notes

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