Water → HCID 13848581, compound

Participants

Reaction Steps

To a solution of 1.128 g of 1-hydroxy-2-(2,3-epoxypropyloxy)-3,4-dichlorobenzene dissolved in 10 ml of ethanol is added 4 ml of 2N sodium hydroxide. The mixture is heated at 80° C. for 5 minutes, to which water is then added and extracted with ether. The organic layer is washed with water, then dried and evaporated to give 1.120 g of the objective 3-hydroxymethyl-7,8-dichloro-1,4-benzodioxane (IIb) as an oil. Yield 99%.

Provenance & Evidence