HCID 178501441, compound → HCID 178501449, compound

Participants

Reaction Steps

470 mg of Boc-Pro-His-Pro-Phe-His-Sta-Val-Tyr-Lys(Boc)-OMe are dissolved at 25° in 2.3 ml of 95% strength TFA and the whole is left to stand for 30 minutes. The H-Pro-His-Pro-Phe-His-Sta-Val-Tyr-Lys-OMe formed is precipitated at 0° in pulverulent form as the trifluoroacetate by the addition of 20 ml of diisopropyl ether, is filtered off and dried; Rf (C)=0.36; Rf (D)=0.24.

Provenance & Evidence