Carbon Dioxide → HCID 178501416, compound

Participants

Reaction Steps

2.5 g of Z-Arg-Pro-Phe-His-OMe are dissolved in 25 ml of 95% strength methanol and, after the addition of 250 mg of Pd-on-carbon, hydrogenated with CO2 -absorption until saturation. The catalyst is filtered off and the filtrate is concentrated to dryness, yielding H-Arg-Pro-Phe-His-OMe in the form of an amorphous powder; Rf (E)=0.05; Rf (C)=0.3.

Provenance & Evidence