反应详情

In a similar manner as above, 6,11-dihydro-11-hydroxydibenz[b,e]oxepin-2-carboamide IX was prepared from the oxepin-carboamide VIII in a quantitative yield. Recrystallization from tetrahydrofuran gave pure crystals having a melting point of 257°-258° C. IR spectrum (KBr tablet, cm-1): 3350, 3180, 1665, 1625, 1410, 1255; NMR spectrum (CDCl3 +d6DMSO, δ-value, ppm): 5.10(d, 1H), 5.78, 5.85, 6.09 (each d, total 3H), 6.6-8.1(m, 9H).

1. customRecrystallization from tetrahydrofuran
2. customgave pure crystals