Hydrogen Peroxide → HCID 13604325, compound

Participants

Reaction Steps

3.80 g (13.7 mmoles) of the 2-(3-methoxy-5-methylthio-2-thienyl)-1H-imidazo[4,5-b]pyridine, obtained in Example 1, are dissolved in 80 ml of glacial acid, 1.63 g (14.4 mmoles) of 30% aqueous solution of hydrogen peroxide are added and stirred at room temperature for 30 hours. The solution is concentrated in vacuo, the residue is dissolved in a small amount of water, neutralized with a saturated solution of sodium hydrogen carbonate, and the precipitating crystals are aspirated and dried. Yield: 3.95 g (98%), m.p. (ethanol) 233°-235° C. (dec.).

Provenance & Evidence