HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-((4-Methoxyphenyl)methyl)piperazine → HCID 53740006, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-((4-Methoxyphenyl)methyl)piperazine | HCID 231905 | — |
| Reactant | N-Boc-L-Leucine Hydrate | HCID 12373896 | — |
| Reactant | HCID 13455629 | HCID 13455629 | — |
| Product | HCID 53740006 | HCID 53740006 | 95.5% |
Reaction Steps
Tert-butoxycarbonyl-L-leucine monohydrate (7.47 g) and 1-(4-methoxy-phenylmethyl)piperazine (6.18 g) were condensed in the same manner as employed in the preparation of tert-butyl (s)-1-(4-diphenylmethylpiperazine-1-yl carbonyl)-3-methylbutylcarbamate to yield 12.0 g of tert-butyl (s)-1-[4-(4-methoxyphenylmethyl)piperazine-1-yl carbonyl]-3-methylbutylcarbamate as a colorless amorphous substance (yield: 95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04596803 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-4cce8cf07da94e6ab3f34c2edbda4a39 |
| Source note | uspto-grants-1986_06 |