HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22691111, compound → HCID 13455643, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22691111 | HCID 22691111 | — |
| Reactant | HCID 86740005 | HCID 86740005 | — |
| Product | HCID 13455643 | HCID 13455643 | 92.1% |
Reaction Steps
Monoethyl trans-epoxy succinate (3.52 g) and 1-L-leucyl-4-(2-pyrimidinyl)piperazine (6.10 g) were condensed in the same manner as employed in the preparation of ethyl trans-3-[(s)-3-methyl-1-{4-(2-pyridyl)piperazine-1-yl carbonyl}butylcarbamoyl]oxirane-2-carboxylate to yield 8.50 g of ethyl trans-3-[(s)-3-methyl-1-{4-(2-pyrimidinyl)piperazine-1-yl carbonyl}butylcarbamoyl]oxirane-2-carboxylate (yield: 92.1%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04596803 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-b93415a94a25424eb5ee3ffbe97589ec |
| Source note | uspto-grants-1986_06 |