Sulfuryl chloride → 1-(Chloromethoxy)-3-(trifluoromethyl)benzene

HRID 1982546Notes

Reaction equation

HRID 1982546 reaction equation
ClC1C=CC(S[CH2:9][O:10][C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([C:17]([F:20])([F:19])[F:18])[CH:12]=2)=CC=1.S(Cl)([Cl:24])(=O)=O>>[Cl:24][CH2:9][O:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([C:17]([F:20])([F:19])[F:18])[CH:12]=1

Participants

3

Reactant 2

HCID 24648Sulfuryl chlorideHCID 13097729HCID 13097729, compound

Product 1

HCID 130977331-(Chloromethoxy)-3-(trifluoromethyl)benzeneYield 89%

Procedure

The title compound was prepared as described in Preparation 3 (b) by reaction of 1-(4-chlorophenylthio) methoxy-3-trifluoromethyl-benzene and sulfuryl chloride; yield 89%, b.p. 88°-90° C./15 mmHg. 1H NMR (CDCl3): δ 5.82 (CH2), 7.26 (Ph). MS [70 eV; m/z (% rel.int.)]: 212/210 (10/34,M); 191 (12), 175 (100), 145 (76), 133 (13), 127 (19), 114 (11), 113 (11).

Sources & evidence

ORD record
ord-e3ddcd3579d24cd199f4f8ba65944310
Source dataset
uspto-grants-1986_06
Patent number
US04596870

Reaction notes

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