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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1982584Generated: October 27, 2026

Phenol → N-(2-phenoxyethyl)propionamide

https://huagongshe.com/reaction/1982584

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenolHCID 996—
Reactant2-Ethyl-2-oxazolineHCID 66412—
ProductN-(2-phenoxyethyl)propionamideHCID 1350882390%

Reaction Steps

Adding 2-ethyl-2-oxazoline to hot (150°) phenol and maintaining heating at about 175° for 16 additional hours. The oil is then quenched in water to give N-(2-phenoxyethyl)propionamide (IV) in approximately 90% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04596884
Source datasetuspto-grants-1986_06
ORD IDord-9ec8c6e359054f9d832d0b0e4663c920
Source noteuspto-grants-1986_06