反应详情

A solution prepared by adding 20 g of 4-cyano-4′-hydroxybiphenyl, 20 g of allyl bromide and 25 g of potassium carbonate to 250 ml of 2-butanone was refluxed for 7 hours. Water was added to the reaction solution for liquid-liquid separation, and the organic layer was washed with water and dried with anhydrous magnesium sulfate. The solvent was evaporated away, and the resulting residue was purified through silica gel column chromatography using toluene as an eluent solvent and then further recrystallized from ethanol to obtain 22 g of 4-allyloxy-4′-cyanobiphenyl.

1. customA solution prepared
2. temperaturewas refluxed for 7 hours
3. washthe organic layer was washed with water
4. dry with materialdried with anhydrous magnesium sulfate
5. customThe solvent was evaporated away
6. customthe resulting residue was purified through silica gel column chromatography
7. customfurther recrystallized from ethanol