HRID1982828

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(=O)OC[C@H]1O[C@@H](Oc2ccccc2Cc2ccc(CC#N)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

HCID12085617

未命名化合物

HCID21909275

未命名化合物

PRODUCTS

生成物

HCID12085617

未命名化合物

结构：N#CCc1ccc(Cc2ccccc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

HCID68875018

未命名化合物

PROCEDURE

实验过程

2-(4-Cyanomethylbenzyl)phenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside was prepared in a similar manner to that described in Reference Example 25 using 4-(2-hydroxybenzyl)phenylacetonitrile instead of methyl 4-(2-hydroxybenzyl)benzoate. Then, the title compound was prepared in a similar manner to that described in Reference Example 50 using 2-(4-cyanomethylbenzyl)phenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside instead of 2-(4-methoxycarbonylbenzyl)-phenyl 2,3,4,6-tetra-O-acetyl-BD-glucopyranoside.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c81f7c4a60364e9791bf2ca55a2d46aa
来源数据集: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07541341B2
来源说明: uspto-grants-2009_06

反应 SMILES

[OH:1][C:2]1[CH:17]=[CH:16][CH:15]=[CH:14][C:3]=1[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12]#[N:13])=[CH:7][CH:6]=1.[C:18]([O:21][C@@H:22]1[C@@H:44]([O:45][C:46](=[O:48])[CH3:47])[C@H:43]([O:49][C:50](=[O:52])[CH3:51])[C@@H:42]([CH2:53][O:54][C:55](=[O:57])[CH3:56])[O:41][C@H:23]1[O:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[CH2:31][C:32]1[CH:37]=[CH:36][C:35]([CH2:38][C:39]#[N:40])=[CH:34][CH:33]=1)(=[O:20])[CH3:19]>>[C:18]([O:21][C@@H:22]1[C@@H:44]([O:45][C:46](=[O:48])[CH3:47])[C@H:43]([O:49][C:50](=[O:52])[CH3:51])[C@@H:42]([CH2:53][O:54][C:55](=[O:57])[CH3:56])[O:41][C@H:23]1[O:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[CH2:31][C:32]1[CH:33]=[CH:34][C:35]([CH2:38][C:39]#[N:40])=[CH:36][CH:37]=1)(=[O:20])[CH3:19].[O:1]([C:2]1[CH:17]=[CH:16][CH:15]=[CH:14][C:3]=1[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12]#[N:13])=[CH:7][CH:6]=1)[C@@H:23]1[O:41][C@H:42]([CH2:53][OH:54])[C@@H:43]([OH:49])[C@H:44]([OH:45])[C@H:22]1[OH:21]