HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-t-butyl-1-(chloromethyl)-1H-pyrazole hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-t-butyl-1H-pyrazole-1-ylmethanol | HCID 23149208 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-t-butyl-1-(chloromethyl)-1H-pyrazole hydrochloride | HCID 23149152 | — |
Reaction Steps
1.07 g of 3-t-butyl-1H-pyrazole-1-ylmethanol was dissolved to 140 ml of dichloromethane. 2 ml of thionyl chloride was added to the solution, followed by stirring at room temperature for overnight. The reaction mixture was concentrated under reduced pressure to obtain 1.66 g of 3-t-butyl-1-(chloromethyl)-1H-pyrazole hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07541374B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-71f639c4cb5c455398ba3d9b56928875 |
| Source note | uspto-grants-2009_06 |