Thionyl Chloride → HCID 23149186, compound

HRID 1983002Notes

Reaction equation

HRID 1983002 reaction equation
O[CH2:2][N:3]1[CH:7]=[CH:6][C:5]([CH:8]=[O:9])=[N:4]1.S(Cl)([Cl:12])=O>ClCCl>[ClH:12].[Cl:12][CH2:2][N:3]1[CH:7]=[CH:6][C:5]([CH:8]=[O:9])=[N:4]1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 23149160HCID 23149160, compound

Product 1

HCID 23149186HCID 23149186, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1.21 g of 1-(hydroxymethyl)-3-formyl-1H-pyrazole was dissolved to 50 ml of dichloromethane. 2.4 ml of thionyl chloride was added to the solution, followed by stirring at room temperature for overnight. The reaction mixture was concentrated under reduced pressure to obtain 1.57 g of 1-(chloromethyl)-3-formyl-1H-pyrazole hydrochloride.

Workup

  1. concentrationThe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-47484155c0a14f7485e51d78cdfcb41e
Source dataset
uspto-grants-2009_06
Patent number
US07541374B2

Reaction notes

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