反应详情

温度

130 °C

The mixture of 2.88 g of 3-phenyl-1H-pyrazole, 0.67 g of paraformaldehyde and 0.3 ml of triethylamine was stirred at 130° C. for 5 hours. After the reaction mixture was cooled to room temperature, acetone was added to the reaction mixture. After the mixture was filtered, hexane was added to the filterate to produce a crystal. The crystal was collected to obtain 2.64 g of 3-phenyl-1H-pyrazole-1-ylmethanol.

1. temperatureAfter the reaction mixture was cooled to room temperature
2. filtrationAfter the mixture was filtered
3. additionhexane was added to the filterate
4. customto produce a crystal
5. customThe crystal was collected