反应详情

温度

130 °C

The mixture of 1.88 g of 4-bromo-3-i-propyl-1H-pyrazole, 0.60 g of paraformaldehyde and 0.10 g of triethylamine was stirred at 130° C. for 5 hours. After the reaction mixture was cooled to room temperature, acetone was added to the reaction mixture. The mixture was filtered, and the filtrate was concentrated under reduced pressure to obtain 1.29 g of 4-bromo-3-i-propyl-1H-pyrazole-1-ylmethanol.

1. temperatureAfter the reaction mixture was cooled to room temperature
2. filtrationThe mixture was filtered
3. concentrationthe filtrate was concentrated under reduced pressure