反应详情

温度

130 °C

The mixture of 0.59 g of 4-(trifluoromethyl)-1H-pyrazole and 0.26 g of paraformaldehyde was stirred at 130° C. for 4 hours. After the reaction mixture was cooled to room temperature, acetone was added to the reaction mixture. The mixture was filtered. The residue was concentration under reduced pressure to obtain 0.60 g of 4-(trifluoromethyl)-1H-pyrazole-1-ylmethanol.

1. temperatureAfter the reaction mixture was cooled to room temperature
2. filtrationThe mixture was filtered
3. concentrationconcentration under reduced pressure