Thionyl Chloride → HCID 57712395, compound

Participants

Reaction Steps

2.23 g of 1-(hydroxymethyl)-3-(trifluoromethyl)-4-ethyoxycarbonyl-1H-pyrazole was dissolved to 30 ml of dichloromethane. 1.4 ml of thionyl chloride was added to the solution, followed by stirring at room temperature for overnight. The reaction mixture was concentrated under reduced pressure to obtain 2.38 g of 1-(chloromethyl)-3-(trifluoromethyl)-4-ethoxycarbonyl-1H-pyrazole.

Provenance & Evidence