Sodium Hydroxide → HCID 178441970, compound

Participants

Reaction Conditions

Reaction Steps

The mixture of 2.51 g of 3-t-butyl-1H-1,2,4-triazole, 35 ml of water and 2.5 ml of 50% aqueous solution of sodium hydroxide was cooled to 0° C., then 3.5 g of bromine was added to it. It was stirred at room temperature for 3 hours. The reaction mixture was extracted by ethyl acetate, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The residue was recrystallized from hexane to obtain 3.80 g of 5-bromo-3-t-butyl-1H-1,2,4-triazole.

Provenance & Evidence