Sodium Hydroxide → HCID 178506331, 화합물

참여 물질

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반응 단계

9.30 g of 3-(pentafluoroethyl)-1H-pyrazole was suspended to 90 ml of water, and 6.0 g of 50% aqueous solution of sodium hydroxide was added to the suspension. The mixture was cooled to 0° C., then 8.79 g of bromine was added to the mixture, followed by stirring at room temperature for 7 hours. The reaction mixture was extracted by ethyl acetate. The organic layer was washed with water, dried over anhydrous magnesium salfate, filtered, and concentrated under reduced pressure to obtain 13.72 g of 4-bromo-3-(pentafluoroethyl)-1H-pyrazole.

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