Thionyl Chloride → HCID 23149146, compound

HRID 1983056Notes

Reaction equation

HRID 1983056 reaction equation
[Cl:1][C:2]([Cl:12])([F:11])[S:3][C:4]1[CH:5]=[N:6][N:7]([CH2:9]O)[CH:8]=1.S(Cl)([Cl:15])=O>C(Cl)(Cl)Cl>[Cl:15][CH2:9][N:7]1[CH:8]=[C:4]([S:3][C:2]([Cl:12])([Cl:1])[F:11])[CH:5]=[N:6]1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 23149182HCID 23149182, compound

Product 1

HCID 23149146HCID 23149146, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

0.22 g of 4-{[dichlorofluoromethyl]thio}-1H-pyrazole-1-ylmethanol was dissolved to 10 ml of chloroform. 0.3 ml of thionyl chloride was added to the solution, and refluxed for 4 hours. The reaction mixture was concentrated under reduced pressure to obtain 0.21 g of 1-(chloromethyl)-4-{[dichloro(fluoro)methyl]thio}-1H-pyrazole.

Workup

  1. temperaturerefluxed for 4 hours
  2. concentrationThe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-6b2fd82e842a4c069fd14c3887b6affe
Source dataset
uspto-grants-2009_06
Patent number
US07541374B2

Reaction notes

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