HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxynicotinic acid → HCID 67215639, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxynicotinic acid | HCID 708093 | — |
| Reactant | 5-Methyl-3-phenyl-4-isoxazolecarbohydrazide | HCID 727924 | — |
| Product | HCID 67215639 | HCID 67215639 | 53% |
Reaction Steps
As described for example 2, 5-methyl-3-phenyl-isoxazole-4-carboxylic acid hydrazide (200 mg, 0.92 mmol) was converted using 2-methoxynicotinic acid instead of o-toluic acid to the title compound (SiO2, heptane:ethyl acetate:dichloromethane=60:20:20 to 0:80:20, 163 mg, 53%) which was obtained as a white solid. MS: m/e=335.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07541372B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-a5d87f7a72aa4626830853a47b98b99e |
| Source note | uspto-grants-2009_06 |