Hydrazine hydrate (1:1) → HCID 22261009, compound

HRID 1983528Notes

Reaction equation

HRID 1983528 reaction equation
[F:1][C:2]1[CH:9]=[C:8](F)[C:7]([C:11]([C:13]2[CH:22]=[CH:21][C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:14]=2)=O)=[CH:6][C:3]=1[C:4]#[N:5].O.[NH2:24][NH2:25]>>[F:1][C:2]1[CH:9]=[C:8]2[C:7]([C:11]([C:13]3[CH:22]=[CH:21][C:20]4[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=4)[CH:14]=3)=[N:24][NH:25]2)=[CH:6][C:3]=1[C:4]#[N:5]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 22260691HCID 22260691, compound

Product 1

HCID 22261009HCID 22261009, compound

Procedure

A total of 2.1 g of 2,4-difluoro-5-(naphthalene-2-carbonyl)-benzonitrile was allowed to react with hydrazine monohydrate by the procedure of Production Example II-10-c and thereby yielded 1.6 g of the title compound as a colorless powder.

Sources & evidence

ORD record
ord-4b56817cc272407d9319930eaf85eb29
Source dataset
uspto-grants-2009_06
Patent number
US07541376B2

Reaction notes

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