Hydrazine hydrate (1:1) → HCID 22260837, compound

HRID 1983536Notes

Reaction equation

HRID 1983536 reaction equation
[Br:1][C:2]1[C:3]([F:21])=[CH:4][C:5](F)=[C:6]([C:8]([C:10]2[CH:19]=[CH:18][C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH:11]=2)=O)[CH:7]=1.O.[NH2:23][NH2:24]>>[Br:1][C:2]1[CH:7]=[C:6]2[C:5](=[CH:4][C:3]=1[F:21])[NH:24][N:23]=[C:8]2[C:10]1[CH:19]=[CH:18][C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH:11]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 68418779HCID 68418779, compound

Product 1

HCID 22260837HCID 22260837, compound

Procedure

A total of 7.0 g of (5-bromo-2,4-difluorophenyl)naphthalene-2-yl-methanone obtained in Production Example II-17-a was allowed to react with hydrazine monohydrate by the procedure of Production Example II-10-c and thereby yielded 1.5 g of the title compound as a colorless powder.

Sources & evidence

ORD record
ord-dcd954724b6040b580e8dc88dd41ab84
Source dataset
uspto-grants-2009_06
Patent number
US07541376B2

Reaction notes

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