Benzonitrile, 4-bromo- → HCID 178421612, compound

HRID 1983601Notes

Reaction equation

HRID 1983601 reaction equation
C12CC(CC1)CC2NC1SC(C)C(=O)N=1.BrC1C=CC(C#N)=CC=1.[CH3:25][C:26]1([C:45]2[CH:52]=[CH:51][C:48]([C:49]#[N:50])=[CH:47][CH:46]=2)[S:30][C:29]([NH:31][C@H:32]([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36]C=2C(F)(F)F)[CH3:33])=[N:28][C:27]1=[O:44]>>[CH:34]12[CH2:36][CH:37]([CH2:38][CH2:39]1)[CH2:33][CH:32]2[NH:31][C:29]1[S:30][C:26]([C:45]2[CH:46]=[CH:47][C:48]([C:49]#[N:50])=[CH:51][CH:52]=2)([CH3:25])[C:27](=[O:44])[N:28]=1

Participants

4

Reactant 3

HCID 12162Benzonitrile, 4-bromo-HCID 178435098HCID 178435098, compoundHCID 178461986HCID 178461986, compound

Product 1

HCID 178421612HCID 178421612, compound

Procedure

The title compound was prepared from the reaction of 2-(bicyclo[2.2.1 ]heptan-2-ylamino)-5-methylthiazol-4(5H)-one with 4-bromobenzonitrile using the procedure described for 2a. MS (ESI, pos. ion) m/z: 326 (M+1).

Sources & evidence

ORD record
ord-d5d02001095543c2bd05016660d8eb1a
Source dataset
uspto-grants-2009_06
Patent number
US07541474B2

Reaction notes

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