Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Naphthalic anhydride, 3-nitro- → 2-{2-[(2-hydroxyethyl)amino]4-methoxyphenyl}-5-nitro-1H-benzo-[de]isoquinolin-1,3(2H)-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Naphthalic anhydride, 3-nitro- | HCID 18194 | — |
| 반응물 | N-(2-hydroxyethyl)-5-methoxy-2-aminoaniline | HCID 68830082 | — |
| 용매 | 2-{4-[ethyl(2-hydroxyethyl)amino]phenyl}-6-nitro-1H-benzo[de]isoquinolin-1,3(2H)-dione | HCID 86613406 | — |
| 생성물 | 2-{2-[(2-hydroxyethyl)amino]4-methoxyphenyl}-5-nitro-1H-benzo-[de]isoquinolin-1,3(2H)-dione | HCID 68828355 | — |
반응 단계
The reaction of N-(2-hydroxyethyl)-5-methoxy-2-aminoaniline with 3-nitronaphthalene-1,8-dicarboxylic anhydride in imidazole (synthesis and work-up as in Example 2, Step 1) afforded the product as a dark-red powder. For purification, the crude product in ethanol/acetone was filtered through a bed of silica gel UV/Vis (CHCl3: λmax: 411, 524 nm
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07544215B2 |
| 출처 데이터셋 | uspto-grants-2009_06 |
| ORD ID | ord-0291e992f573475d9f57775214d5b87e |
| 출처 메모 | uspto-grants-2009_06 |