Dimethyl Sulfoxide → HCID 68857251, compound

HRID 1984012Notes

Reaction equation

HRID 1984012 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C@H:3]([CH2:10][CH2:11][N:12]2[CH2:17][CH2:16][CH:15]([C:18]3[CH:19]=[C:20]4[C:24](=[CH:25][CH:26]=3)[NH:23][CH:22]=[CH:21]4)[CH2:14][CH2:13]2)[CH2:2]1.[C:27]([OH:32])(=[O:31])[C:28]([NH2:30])=[O:29].CS(C)=[O:35]>>[C:27]([OH:32])(=[O:31])[C:28]([OH:35])=[O:29].[NH:23]1[C:24]2[C:20](=[CH:19][C:18]([CH:15]3[CH2:14][CH2:13][N:12]([CH2:11][CH2:10][C@H:3]4[C:4]5[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=5)[N:1]([C:27](=[O:31])[C:28]([NH2:30])=[O:29])[CH2:2]4)[CH2:17][CH2:16]3)=[CH:26][CH:25]=2)[CH:21]=[CH:22]1

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 974Oxamic AcidHCID 68855985HCID 68855985, compound

Product 1

HCID 68857251HCID 68857251, compound

Procedure

from 5-{1-[(S)-2-(2,3-dihydro-1H-indol-3-yl)-ethyl]-piperidin-4-yl}-1H-indole and oxalamic acid. Assignment of the optical rotation was done in dimethyl sulfoxide.

Sources & evidence

ORD record
ord-4ee1b661ad6c4bfea89bc07e4ca880b1
Source dataset
uspto-grants-2009_06
Patent number
US07544685B2

Reaction notes

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