HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984028Generated: November 1, 2026
Hydrochloric Acid → HCID 178456383, compound
https://huagongshe.com/reaction/1984028
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 178456384 | HCID 178456384 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178456383 | HCID 178456383 | 125.8% |
Reaction Steps
A mixture of 440 mg (0.90 mmol) of trans-N′-{4-[4-(4-Isopropyl-piperazine-1-carbonyl)-cyclohexyloxy]-benzoyl}-hydrazinecarboxylic acid tert-butyl ester, 1.53 ml (6.12 mmol) of 4M hydrochloric acid in 1,4-dioxane solution and 4 ml of methanol was stirred for 4 h at 40° C. The mixture was evaporated to dryness to yield 0.44 g of the title compound. MS (m/e): 389.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07544683B2 |
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| Source dataset | uspto-grants-2009_06 |
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| ORD ID | ord-8e5133f91dc140a7837cf2431bbc3458 |
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| Source note | uspto-grants-2009_06 |
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