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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984028Generated: November 1, 2026

Hydrochloric Acid → HCID 178456383, compound

https://huagongshe.com/reaction/1984028

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 178456384HCID 178456384—
SolventMethanolHCID 887—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 178456383HCID 178456383125.8%

Reaction Conditions

Temperature40 °C

Reaction Steps

A mixture of 440 mg (0.90 mmol) of trans-N′-{4-[4-(4-Isopropyl-piperazine-1-carbonyl)-cyclohexyloxy]-benzoyl}-hydrazinecarboxylic acid tert-butyl ester, 1.53 ml (6.12 mmol) of 4M hydrochloric acid in 1,4-dioxane solution and 4 ml of methanol was stirred for 4 h at 40° C. The mixture was evaporated to dryness to yield 0.44 g of the title compound. MS (m/e): 389.2 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544683B2
Source datasetuspto-grants-2009_06
ORD IDord-8e5133f91dc140a7837cf2431bbc3458
Source noteuspto-grants-2009_06