Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984167Generated: November 2, 2026

4-(4-Nitrophenyl)piperazin-1-ylethylamine → 1-t-Butyl-3-{2-[4-(4-nitrophenyl)piperazin-1-yl]ethyl}aminomethyl-5-propylpyrazole

https://huagongshe.com/reaction/1984167

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Nitrophenyl)piperazin-1-ylethylamineHCID 28913887—
Reactant5-Propyl-1-t-butylpyrazole-3-carbaldehydeHCID 86261095—
Product1-t-Butyl-3-{2-[4-(4-nitrophenyl)piperazin-1-yl]ethyl}aminomethyl-5-propylpyrazoleHCID 1603877995.6%

Reaction Steps

Compound 50 was prepared using the same method as that of Example 1 except that 4-(4-nitrophenyl)piperazin-1-ylethylamine and 5-propyl-1-t-butylpyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-99bb109aa17e4f569b713399e80bd9d3
Source noteuspto-grants-2009_06