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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984169Generated: November 3, 2026

1-Tert-butyl-5-iso-butyl-3-formylpyrazole → 1-t-Butyl-5-iso-butyl-3-{2-[4-(4-nitrophenyl)piperazin-1-yl]ethyl}aminomethylpyrazole

https://huagongshe.com/reaction/1984169

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Tert-butyl-5-iso-butyl-3-formylpyrazoleHCID 22493583—
Reactant4-(4-Nitrophenyl)piperazin-1-ylethylamineHCID 28913887—
Product1-t-Butyl-5-iso-butyl-3-{2-[4-(4-nitrophenyl)piperazin-1-yl]ethyl}aminomethylpyrazoleHCID 1603878174.5%

Reaction Steps

Compound 52 was prepared using the same method as that of Example 1 except that 4-(4-nitrophenyl)piperazin-1-ylethylamine and 1-t-butyl-5-iso-butylpyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-0a7e506f9eaa4a4488cc24c4eda5aff5
Source noteuspto-grants-2009_06