Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984173Generated: November 3, 2026

4-(4-Nitrophenyl)piperazin-1-ylethylamine → 1-t-Butyl-5-(4-methylphenyl)-3-{2-[4-(4-nitrophenyl)piperazin-1-yl]ethyl}aminomethylpyrazole

https://huagongshe.com/reaction/1984173

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Nitrophenyl)piperazin-1-ylethylamineHCID 28913887—
Reactant1-t-Butyl-5-(4-methylphenyl)pyrazole-3-carbaldehydeHCID 86611059—
Product1-t-Butyl-5-(4-methylphenyl)-3-{2-[4-(4-nitrophenyl)piperazin-1-yl]ethyl}aminomethylpyrazoleHCID 1603885369.4%

Reaction Steps

Compound 56 was prepared using the same method as that of Example 1 except that 4-(4-nitrophenyl)piperazin-1-ylethylamine and 1-t-butyl-5-(4-methylphenyl)pyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-a1997f9a20ab462b8bee9fcd23f10ddc
Source noteuspto-grants-2009_06