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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984176Generated: November 2, 2026

2-[4-(2-Fluorophenyl)piperazin-1-yl]ethanamine → 1-t-Butyl-3-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}aminomethyl-5-propyl pyrazole

https://huagongshe.com/reaction/1984176

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[4-(2-Fluorophenyl)piperazin-1-yl]ethanamineHCID 11009581—
Reactant5-Propyl-1-t-butylpyrazole-3-carbaldehydeHCID 86261095—
Product1-t-Butyl-3-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}aminomethyl-5-propyl pyrazoleHCID 1603893076.7%

Reaction Steps

Compound 62 was prepared using the same method as Example 1 except that 4-(2-fluorophenyl)piperazin-1-ylethylamine and 5-propyl-1-t-butylpyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-76ea09f21f1747a5a3bb15b9dbf71aa4
Source noteuspto-grants-2009_06