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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984182Generated: October 27, 2026

2-[4-(2-Fluorophenyl)piperazin-1-yl]ethanamine → 1,5-Diphenyl-3-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}aminomethylpyrazole

https://huagongshe.com/reaction/1984182

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[4-(2-Fluorophenyl)piperazin-1-yl]ethanamineHCID 11009581—
Reactant1,5-Diphenyl-1H-pyrazole-3-carbaldehydeHCID 53407084—
Product1,5-Diphenyl-3-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}aminomethylpyrazoleHCID 1603892574.5%

Reaction Steps

Compound 68 was prepared using the same method as that of Example 1 except that 4-(2-fluorophenyl)piperazin-1-ylethylamine and 1,5-diphenylpyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-309a9cba3d9a40cb8d624c2d5d36c4ff
Source noteuspto-grants-2009_06