HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[4-(2-Fluorophenyl)piperazin-1-yl]ethanamine → 1-t-Butyl-5-(4-chlorophenyl)-3-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}aminomethylpyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[4-(2-Fluorophenyl)piperazin-1-yl]ethanamine | HCID 11009581 | — |
| Reactant | 5-(4-Chlorophenyl)-1-t-butylpyrazole-3-carbaldehyde | HCID 86611060 | — |
| Product | 1-t-Butyl-5-(4-chlorophenyl)-3-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}aminomethylpyrazole | HCID 16038857 | 74.2% |
Reaction Steps
Compound 70 was prepared using the same method as that of Example 1 except that 4-(2-fluorophenyl)piperazin-1-ylethylamine and 5-(4-chlorophenyl)-1-t-butylpyrazole-3-carbaldehyde were used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544686B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-1bfaf20eb2944b23b8080ded050ce99c |
| Source note | uspto-grants-2009_06 |