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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984185Generated: November 3, 2026

2-[4-(2-Fluorophenyl)piperazin-1-yl]ethanamine → 5-(4-Cyclohexylphenyl)-3-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}aminomethyl-1-phenylpyrazole

https://huagongshe.com/reaction/1984185

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[4-(2-Fluorophenyl)piperazin-1-yl]ethanamineHCID 11009581—
Reactant5-(4-Cyclohexylphenyl)-1-phenylpyrazole-3-carbaldehydeHCID 86261131—
Product5-(4-Cyclohexylphenyl)-3-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}aminomethyl-1-phenylpyrazoleHCID 1603899764.8%

Reaction Steps

Compound 71 was prepared using the same method as that of Example 1 except that 4-(2-fluorophenyl)piperazin-1-ylethylamine and 5-(4-cyclohexylphenyl)-1-phenyl pyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-0ba99d87fd6b4512b76c72721ba2bb62
Source noteuspto-grants-2009_06