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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984201Generated: October 25, 2026

4-(4-Chlorobenzhydryl)piperazin-1-ylethylamine → 1-t-Butyl-3-{2-[4-(4-chlorobenzhydryl)piperazin-1-yl]ethyl}aminomethyl-5-(4-chlorophenyl)pyrazole

https://huagongshe.com/reaction/1984201

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Chlorobenzhydryl)piperazin-1-ylethylamineHCID 14210620—
Reactant5-(4-Chlorophenyl)-1-t-butylpyrazole-3-carbaldehydeHCID 86611060—
Product1-t-Butyl-3-{2-[4-(4-chlorobenzhydryl)piperazin-1-yl]ethyl}aminomethyl-5-(4-chlorophenyl)pyrazoleHCID 6897390557%

Reaction Steps

Compound 100 was prepared using the same method as that of Example 1 except that 4-(4-chlorobenzhydryl)piperazin-1-ylethylamine and 5-(4-chlorophenyl)-1-t-butyl pyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-433c65cf742a4c4c925d51b5553585d5
Source noteuspto-grants-2009_06