Azepane → HCID 44409787, compound

HRID 1984315Notes

Reaction equation

HRID 1984315 reaction equation
Cl[C:2]1[N:7]=[C:6]([CH:8]2[CH2:10][CH2:9]2)[N:5]=[C:4]([NH:11][CH:12]2[CH2:14][CH2:13]2)[C:3]=1[N+:15]([O-:17])=[O:16].[NH:18]1[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[N:18]1([C:2]2[N:7]=[C:6]([CH:8]3[CH2:10][CH2:9]3)[N:5]=[C:4]([NH:11][CH:12]3[CH2:14][CH2:13]3)[C:3]=2[N+:15]([O-:17])=[O:16])[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 8119AzepaneHCID 10149233HCID 10149233, compound

Product 1

HCID 44409787HCID 44409787, compound

Procedure

6-(1-azepanyl)-N,2-dicyclopropyl-5-nitro-4-pyrimidinamine 197 was synthesized as described in 7.1 using 6-chloro-N,2-dicyclopropyl-5-nitro-4-pyrimidinamine 44 and azepane as starting material.

Sources & evidence

ORD record
ord-81b6e261a9964d8f9b5671d6c498c6dc
Source dataset
uspto-grants-2009_06
Patent number
US07544675B2

Reaction notes

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