HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-iodo-1H-imidazole → HCID 24784183, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-iodo-1H-imidazole | HCID 2773468 | — |
| Reactant | 4-Ethynyl-5-methyl-3-phenyl-isoxazole | HCID 53434647 | — |
| Product | HCID 24784183 | HCID 24784183 | 77% |
Reaction Steps
As described for example 11c, 4-ethynyl-5-methyl-3-phenyl-isoxazole (79 mg, 0.43 mmol) was converted (using 2-iodo-1H-imidazole instead of 2-chloro-4-iodopyridine) to the title compound (SiO2, heptane:ethyl acetate=95:5 to 0:100, 83 mg, 77%) which was obtained as an off-white solid. MS: m/e=250.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544704B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-ad1c4ac150f444a9bf7e449cf65e2133 |
| Source note | uspto-grants-2009_06 |