HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-3-methylpyridine → HCID 24783917, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-3-methylpyridine | HCID 220832 | — |
| Reactant | 4-Ethynyl-5-methyl-3-phenyl-isoxazole | HCID 53434647 | — |
| Product | HCID 24783917 | HCID 24783917 | 66% |
Reaction Steps
As described for example 11c, 4-ethynyl-5-methyl-3-phenyl-isoxazole (92 mg, 0.50 mmol) was converted (using 2-bromo-3-methylpyridine instead of 2-chloro-4-iodopyridine) to the title compound (SiO2, heptane:ethyl acetate=95:5 to 0:100, 91 mg, 66%) which was obtained as a light yellow solid. MS: m/e=275.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544704B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-e4b3874a6f9e416dbd3dbd2f7b8eaaa8 |
| Source note | uspto-grants-2009_06 |