Potassium Carbonate → HCID 21921667, compound

HRID 1984800Notes

Reaction equation

HRID 1984800 reaction equation
C[O:2][C:3](=[O:12])[C:4]1[CH:9]=[C:8]([Br:10])[CH:7]=[CH:6][C:5]=1[OH:11].I[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].C(=O)([O-])[O-].[K+].[K+]>>[Br:10][C:8]1[CH:7]=[CH:6][C:5]([O:11][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])=[C:4]([CH:9]=1)[C:3]([OH:2])=[O:12]

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 202741-IodoheptaneHCID 77683Methyl 5-bromosalicylate

Product 1

HCID 21921667HCID 21921667, compound

Procedure

5-Bromo-2-heptyloxy-benzoic acid was prepared by reacting 5-bromo-2-hydroxy-benzoic acid methyl ester (1.0 g, 4.32 mmol) with iodoheptane (1.46 g, 6.49 mmol) as per general procedure H with potassium carbonate (1.5 g, 10.8 mmol) added. The ester thus obtained was subjected to hydrolysis as per general procedure C to yield the 5-bromo-2-heptyloxy-benzoic acid (0.950 g).

Workup

  1. additionadded

Sources & evidence

ORD record
ord-eb17ca7bfee54bd18e9ba677a5e7a1d9
Source dataset
uspto-grants-2009_06
Patent number
US07544699B2

Reaction notes

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