HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 11721387, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | HCID 57717651 | HCID 57717651 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 11721387 | HCID 11721387 | 75.7% |
Reaction Steps
3-Biphenyl-4-yl-(2S)-{[6-(4-tert-butyl-phenoxy)-3-ethylsulfanyl-quinoxaline-2-carbonyl]-amino}-propionic acid methyl ester (30 mg, 0.048 mmol) was hydrolyzed as described in general procedure C. Column chromatography over silica using DCM and 95:5 DCM-methanol as eluants gave the title compound (22 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544699B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-a1caa4c330a04a0098a35076f3290ad9 |
| Source note | uspto-grants-2009_06 |