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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984840Generated: November 1, 2026

(S)-Methyl 3-([1,1'-biphenyl]-4-yl)-2-aminopropanoate → HCID 57717698, compound

https://huagongshe.com/reaction/1984840

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-Methyl 3-([1,1'-biphenyl]-4-yl)-2-aminopropanoateHCID 15714801—
ReactantHCID 18457633HCID 18457633—
ProductHCID 57717698HCID 5771769893.1%

Reaction Steps

50 mg (0.12 mmol) of 7-(4-tert-butyl-phenoxy)-1-cyclopentylmethyl-isoquinoline-3-carboxylic acid was reacted with (2S)-amino-3-biphenyl-4-yl-propionic acid methyl ester (34.8 mg, 0.13 mmol) as described in general procedure A. The resulting ester was hydrolyzed as described in general procedure C to afford 70 mg of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544699B2
Source datasetuspto-grants-2009_06
ORD IDord-2e9cd920e5144fc2ba4d436e24dc8717
Source noteuspto-grants-2009_06