Dimethylformamide → 1-O-[[5-(2-amino-6-oxo-3H-purin-9-yl)-3-fluorooxolan-2-yl]methyl] 4-O-[2,3-bis[[3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]oxy]propyl] butanedioate
Reaction equation
[C:30](=[O:31])([O:32][CH2:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1)[NH:40][CH:41]([CH:42]([CH3:43])[CH3:44])[C:45](=[O:46])[O:47][CH:48]([CH2:49][O:50][C:51]([CH2:52][CH2:53][C:54](=[O:55])[OH:56])=[O:57])[CH2:58][O:59][C:60]([CH:61]([NH:62][C:63](=[O:64])[O:65][CH2:66][c:67]1[cH:68][cH:69][cH:70][cH:71][cH:72]1)[CH:73]([CH3:74])[CH3:75])=[O:76].[CH:77]1([N:78]=[C:79]=[N:80][CH:81]2[CH2:82][CH2:83][CH2:84][CH2:85][CH2:86]2)[CH2:87][CH2:88][CH2:89][CH2:90][CH2:91]1.[F:1][CH:2]1[CH2:3][CH:4]([n:9]2[cH:10][n:11][c:12]3[c:13](=[O:14])[nH:15][c:16]([NH2:17])[n:18][c:19]23)[O:5][CH:6]1[CH2:7][OH:8].[O:92]=[CH:93][N:94]([CH3:95])[CH3:96].[OH:20][n:21]1[c:22]2[c:23]([cH:24][cH:25][cH:26][cH:27]2)[n:28][n:29]1>>[F:1][CH:2]1[CH2:3][CH:4]([n:9]2[cH:10][n:11][c:12]3[c:13](=[O:14])[nH:15][c:16]([NH2:17])[n:18][c:19]23)[O:5][CH:6]1[CH2:7][O:8][C:54]([CH2:53][CH2:52][C:51]([O:50][CH2:49][CH:48]([O:47][C:45]([CH:41]([NH:40][C:30](=[O:31])[O:32][CH2:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1)[CH:42]([CH3:43])[CH3:44])=[O:46])[CH2:58][O:59][C:60]([CH:61]([NH:62][C:63](=[O:64])[O:65][CH2:66][c:67]1[cH:68][cH:69][cH:70][cH:71][cH:72]1)[CH:73]([CH3:74])[CH3:75])=[O:76])=[O:57])=[O:55]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-1c23bc4a6f78424aa8e69c81278fc3a2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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