HCID 68850270, compound → HCID 86610864, compound

Participants

Reaction Steps

To a solution of N2-(1-benzyl-piperidin-4-yl)-N4,N4-dimethyl-quinazoline-2,4-diamine (1.80 g, 4.98 mmol) in MeOH (18 mL) was added 20% Pd(OH)2 (360 mg). The mixture was stiffed at 50° C. under hydrogen atmosphere for 3 days, filtered through a pad of celite, and concentrated to give N4,N4-dimethyl-N2-piperidin-4-yl-quinazoline-2,4-diamine (1.33 g, 99%) as a pale yellow solid.

Provenance & Evidence