反应详情

3-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-2-ethyl-6-fluoro-1H-indole (1.4 g) is hydrogenated for 1 hour (r.t./1013 mbar) in the presence of 10% Pd/C catalyst (0.3 g) and methanol (25 ml). The catalyst is removed by filtration, the solvent evaporated and the residue washed with small portions of ether. 1.2 g (85%) of pure product is obtained.

1. custom(r.t./1013 mbar)
2. customThe catalyst is removed by filtration
3. customthe solvent evaporated
4. washthe residue washed with small portions of ether