Sodium Carbonate → 9,12,15-Octadecatrienoic acid, sodium salt, (Z,Z,Z)-

HRID 1984989Notes

Reaction equation

HRID 1984989 reaction equation
[C:1]([OH:20])(=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]/[CH:9]=[CH:10]\[CH2:11]/[CH:12]=[CH:13]\[CH2:14]/[CH:15]=[CH:16]\[CH2:17][CH3:18].C(=O)([O-])[O-].[Na+:25].[Na+]>O>[Na+:25].[C:1]([O-:20])(=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]/[CH:9]=[CH:10]\[CH2:11]/[CH:12]=[CH:13]\[CH2:14]/[CH:15]=[CH:16]\[CH2:17][CH3:18]

Participants

4

Reactant 2

HCID 10340Sodium CarbonateHCID 5280934Linolenic Acid3×

Product 1

HCID 236766679,12,15-Octadecatrienoic acid, sodium salt, (Z,Z,Z)-

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

α-Linolenic acid serving as a starting material has considerably low water solubility. Therefore, in order to cause α-linolenic acid to function effectively as an enzyme substrate, an α-linolenic acid sodium salt was prepared. Specifically, sodium carbonate (530 mg) was dissolved in purified water (10 mL), and then heated to 55° C. α-Linolenic acid (product of Nacalai Tesque, Inc.) (278 mg) was added dropwise to the resultant solution, and the mixture was stirred for three hours.

Sources & evidence

ORD record
ord-b0c60b89d1934ad8a25b63749b6b7b42
Source dataset
uspto-grants-2009_06
Patent number
US07544821B2

Reaction notes

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