反应详情

2-(4-{2-[1-(4-Methoxy-benzyl)-3-methyl-2-oxo-imidazolidin-4-yl]-ethoxy}-2-methyl-phenoxy)-2-methyl-propionic acid ethyl ester (0.105 g, 0.217 mmole) is treated with tryethylsilane (0.064 g, 0.743 mmole) in TFA (8.0 mL) at room temperature for about 6 hours. After evaporating the solvents, the residue is purified using silica gel (0-50% acetone/hexane). Colorless oil (0.041 g, 51%). Mass [EI+] 365 (M+H)+, 729 (2M+H)+.

1. customAfter evaporating the solvents
2. customthe residue is purified