Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1985348Generated: October 26, 2026

4-Methylphenyl isocyanate → Dimethyl 2-(3-{2-[(4-toluidinocarbonyl)oxy]ethyl}benzyl)malonate

https://huagongshe.com/reaction/1985348

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methylphenyl isocyanateHCID 69325—
ReactantDimethyl 2-[3-(2-hydroxyethyl)benzyl]malonateHCID 22926790—
ProductDimethyl 2-(3-{2-[(4-toluidinocarbonyl)oxy]ethyl}benzyl)malonateHCID 57719522—

Reaction Steps

Using dimethyl 2-[3-(2-hydroxyethyl)benzyl]malonate and p-tolylisocyanate, the title compound was obtained in the same manner as described in Example 192b).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544835B2
Source datasetuspto-grants-2009_06
ORD IDord-84cda545b5c64426be01ed520ae8f06f
Source noteuspto-grants-2009_06