4-(Trifluoromethyl)phenyl isocyanate → HCID 57719378, compound

HRID 1985363Notes

Reaction equation

HRID 1985363 reaction equation
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:16]=[CH:17][C:18]=1[O:19][CH3:20])[CH2:6][CH:7]([C:12]([O:14][CH3:15])=[O:13])[C:8]([O:10][CH3:11])=[O:9].[F:21][C:22]([F:33])([F:32])[C:23]1[CH:28]=[CH:27][C:26]([N:29]=[C:30]=[O:31])=[CH:25][CH:24]=1>>[F:21][C:22]([F:32])([F:33])[C:23]1[CH:28]=[CH:27][C:26]([NH:29][C:30]([O:1][CH2:2][C:3]2[CH:4]=[C:5]([CH:16]=[CH:17][C:18]=2[O:19][CH3:20])[CH2:6][CH:7]([C:8]([O:10][CH3:11])=[O:9])[C:12]([O:14][CH3:15])=[O:13])=[O:31])=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 737684-(Trifluoromethyl)phenyl isocyanateHCID 22926839Dimethyl 2-(3-(hydroxymethyl)-4-methoxybenzyl]malonate

Product 1

HCID 57719378HCID 57719378, compound

Procedure

Using dimethyl 2-[3-(hydroxymethyl)-4-methoxybenzyl]malonate and α,α,α-trifluoro-p-tolylisocyanate, the title compound was obtained in the same manner as described in Example 192b).

Sources & evidence

ORD record
ord-9000687467f84cf3b087650cb45005d5
Source dataset
uspto-grants-2009_06
Patent number
US07544835B2

Reaction notes

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