1-Isocyanato-4-methoxybenzene → Dimethyl 2-[4-ethoxy-3-({[(4-methoxyanilino)carbonyl]oxy}methyl)benzyl]malonate

HRID 1985374Notes

Reaction equation

HRID 1985374 reaction equation
[CH2:1]([O:3][C:4]1[CH:19]=[CH:18][C:7]([CH2:8][CH:9]([C:14]([O:16][CH3:17])=[O:15])[C:10]([O:12][CH3:13])=[O:11])=[CH:6][C:5]=1[CH2:20][OH:21])[CH3:2].[CH3:22][O:23][C:24]1[CH:29]=[CH:28][C:27]([N:30]=[C:31]=[O:32])=[CH:26][CH:25]=1>>[CH2:1]([O:3][C:4]1[CH:19]=[CH:18][C:7]([CH2:8][CH:9]([C:14]([O:16][CH3:17])=[O:15])[C:10]([O:12][CH3:13])=[O:11])=[CH:6][C:5]=1[CH2:20][O:21][C:31]([NH:30][C:27]1[CH:28]=[CH:29][C:24]([O:23][CH3:22])=[CH:25][CH:26]=1)=[O:32])[CH3:2]

Participants

3

Reactant 2

HCID 794431-Isocyanato-4-methoxybenzeneHCID 22926717Dimethyl 2-[4-ethoxy-3-(hydroxymethyl)benzyl]malonate

Product 1

HCID 57719745Dimethyl 2-[4-ethoxy-3-({[(4-methoxyanilino)carbonyl]oxy}methyl)benzyl]malonate

Procedure

Using dimethyl 2-[4-ethoxy-3-(hydroxymethyl)benzyl]malonate and 4-methoxyphenylisocyanate, the title compound was obtained in the same manner as described in Example 192b).

Sources & evidence

ORD record
ord-ccc771b8b6bb4ace9cd81b20b02f3d6a
Source dataset
uspto-grants-2009_06
Patent number
US07544835B2

Reaction notes

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